High prices and funding cuts stall HIV prevention revolution

Source: United Nations 2

By Felipe de Carvalho

Health

The AIDS epidemic could stage a comeback amid unequal access to breakthrough prevention medicines and a sharp decline in global funding, according to a UN report released on Monday ahead of the opening of the 26th International AIDS Conference in Rio de Janeiro, Brazil.

Why it matters

  • 1.2 million people acquired HIV and 570,000 died from AIDS-related illnesses in 2025
  • 22 per cent of people living with HIV are still not receiving treatment
  • International HIV funding fell 18 per cent, the steepest decline in nearly 20 years
  • Such new medicines as lenacapavir are nearly 100 per cent effective at preventing HIV infection
  • 20 million people need access to antiretroviral-based prevention to make a meaningful impact on the epidemic
  • Generic versions of lenacapavir could cost as little as $40 per person per year, but they will remain unavailable in many countries

Defined by a paradox

The conference, taking place in Rio from 27 to 31 July, is defined by a paradox.

By the end of this decade, more than three million people could become infected with HIV, yet the tools to stop this crisis already exist, from groundbreaking prevention medicines to community-led interventions with a proven track record. What is missing is sustained financing.

This growing funding gap is already forcing countries to cut essential services and close community organizations, according to the new report from UNAIDS, the agency working to end the epidemic by 2030. 

Unless urgent action is taken, the agency warns, the world is on course for a resurgence of the epidemic.

That contradiction defines the 26th International AIDS Conference.

On the one side stands a revolution in HIV prevention, with a new generation of medicines now offering protection against HIV comparable to that of a vaccine.

On the other is a growing concern that these breakthroughs will remain out of reach for millions because they are priced too high and controlled by pharmaceutical patent holders.

Brazil excluded from generic production

Few countries illustrate this paradox more clearly than the conference host itself.

Although Brazil played a key role in the clinical trials that helped bring lenacapavir to market, it was excluded from the list of countries authorised to manufacture lower-cost generic versions.

Lenacapavir is a long-acting injectable medicine that requires just two injections a year and prevents HIV infection in nearly 100 per cent of cases, according to the latest studies.

Universal access is ‘distant reality’ for most

Equitable and universal access remains a distant reality for millions of people because of high prices and the exclusion of many countries from voluntary licensing agreements,” said Variano Terto Jr., vice president of the Brazilian Interdisciplinary AIDS Association (ABIA).

He was speaking at a conference side event organized by the Community of Portuguese Language Countries (CPLP). 

He added that patents on essential drugs have been “reinforcing monopolies and privatization of public knowledge”.

One of the conference co-organizers, ABIA recently published a study showing that Brazil could manufacture lenacapavir domestically for approximately $75 per patient per year. 

By contrast, the patented version costs more than $20,000, a price considered unsustainable for Brazil’s public health system.

Risk of injustice

The true measure of success is not whether medicines exist, but whether the people who need them can actually obtain them and at an affordable price, said UNAIDS Executive Director Winnie Byanyima.

Innovation without access is not innovation; it is injustice,” she said.

UNAIDS estimates that 20 million people need access to antiretroviral-based prevention if the world is to significantly reduce new HIV infections.

© UNDP A safe space for HIV/AIDS support in Lahore, Pakistan, where marginalised communities gather for health awareness and social support.

Calls for new funding model

While HIV infections and AIDS-related deaths are at their lowest levels in more than three decades, the global response remains dangerously fragile.

International HIV financing dropped by more than $1.5 billion between 2024 and 2025, an 18 per cent decline that marked its lowest level in nearly two decades, and global development assistance fell by 23 per cent last year, the largest annual decline ever recorded, with health programmes, including HIV initiatives, among the hardest hit.

Meanwhile, new HIV infections increased across three regions and in 21 countries during 2025.

The current moment should be understood as “the end of the era of dependence on international aid”, the UNAIDS chief said, calling for a new financing model, including measures such as sovereign debt restructuring, to enable governments to invest in “the future of their people”.

Guterres: Fast-tracking West Bank outposts is a ‘flagrant violation’ of international law

Source: United Nations 2

Peace and Security

The United Nations continues to monitor developments in the Occupied Palestinian Territory amid rising violence and greater restrictions in the occupied West Bank.

On Monday, UN Secretary-General António Guterres expressed deep concern over Israel’s recent announcement of a series of measures in response to recent attacks. 

These include accelerating the process to legalise farm outposts in the West Bank and establish new ones.   

Settlements are illegal 

The Secretary-General reiterated that all settlements, including outposts, have no legal validity and constitute a flagrant violation of international law

Moreover, they remain a major obstacle to achieving the two-State solution between Israelis and Palestinians, and a just, lasting and comprehensive peace.

The UN humanitarian affairs office OCHA voiced alarm over the escalating violence across the West Bank in recent days. 

Death, destruction and restrictions 

Since Thursday, at least eight Palestinians – including a child – as well as two Israelis, have been killed and many others have been injured.  

Homes, mosques, trees and agriculture structures have been set ablaze or otherwise vandalized and, in some cases, destroyed. At least 10 Palestinian families have been displaced.

“In parallel, Israeli forces have tightened their restrictions on Palestinian movements and access across many areas of the West Bank, preventing thousands of people from reaching essential services, such as emergency medical care and the sources of their livelihoods,” OCHA said. 

Since January, the agency has documented more than 1,330 incidents involving Israeli settlers that resulted in casualties, property damage or both.

As of Saturday, Israeli forces or settlers have killed 77 Palestinians this year, including 18 children.  During the same period, three Israelis were killed by Palestinians. 

Meanwhile, the UN and partners continue to call for the urgent protection of civilians and strict respect for both international humanitarian law and international human rights law, underscoring that perpetrators must be held to account. 

Lebanon: Israeli strikes ‘could amount to international crimes,’ warns Türk

Source: United Nations 2

Peace and Security

UN Human Rights Chief Volker Türk expressed concern about ongoing displacement and destruction caused by Israeli strikes against Lebanon as he concluded a two-day visit to the country on Monday.

Lebanon faces crises including delayed elections, economic collapse and conflict. More than 4,300 people have been killed and 12,200 more have been injured in Lebanon since Iran-backed Hezbollah militants joined the regional war triggered by US-Israeli attacks on 2 March, according to national authorities.

“I am concerned that the overall conduct resulting in large scale displacement and denial of returns could amount to international crimes,” Mr. Türk said at a press conference in the capital Beirut on Monday.

Seeing displacement up close

While in Lebanon, Mr. Türk met representatives from the Lebanese Government, civil society groups, national human rights mechanisms and people who were forced to flee their homes because of the conflict.

Despite a 17 April conditional ceasefire agreed by Israel and the Lebanese Government reached via US-led talks, Israel has continued to conduct airstrikes and use explosive weapons in densely populated areas while Hezbollah has likewise continued fighting, leading to mass displacement, according to the UN’s human rights office (OHCHR).

At a school repurposed as a shelter for around 1,000 people fleeing violence, civilians told Mr. Türk how their homes, schools, healthcare facilities, water distribution networks, electricity infrastructure, places of worship and agricultural land had been destroyed by Israeli strikes.

A man who lost both his mother and brother in Israeli attacks that destroyed their Beirut home said he is now working to document rights violations and is seeking accountability, Mr. Türk recounted.

“I am struck by the widespread damage and compounded suffering that I have seen,” Mr. Türk said. “The trauma, frustration and despair are palpable – but so too is the demand for justice which I heard resoundingly.”

UN News UN Human Rights Chief Volker Türk visited Lebanon on Sunday and Monday, meeting with government, civil society and displaced people. ©OHCHR

With the consent of Lebanon’s government, the UN human rights office recently deployed a mission to Lebanon to collect information and evidence on alleged human rights and humanitarian violations committed by all parties to the conflict.

The UN Interim Force in Lebanon (UNIFIL)’s mandate will expire at the end of this year. The peacekeepers’ absence could pose new risks for civilians in southern Lebanon, Mr. Türk warned.

Progress is possible

In meetings with civil society organisations, Mr. Türk said local leaders highlighted the need for stronger protections for marginalised groups including refugees, migrants, LGBTQ+ people and people with disabilities.

Mr. Türk said he heard “heartbreaking” stories from these leaders about people with disabilities who struggled to evacuate to safety or access emergency shelters.

However, he recognised Lebanon’s progress on several issues, including ratifying the Convention on the Rights of Persons with Disabilities and proposing measures that would abolish the death penalty and strengthen judicial independence and the rule of law.

He further called for improvements to prison conditions and the decriminalisation of same-sex relationships.

Recovering from the current conflict will be complex, Mr. Türk said, as it will take time for communities to trust the government to protect their rights and provide the services, safety and security they need.

“My office and my colleagues here on the ground remain ready to support Lebanon in the promotion and protection of human rights for all,” he said.

Gaza: Dialysis patients face gruelling hospital journey by donkey cart

Source: United Nations 2

Health

Shortly before sunrise, Palestinian Fathi Hajji begins an arduous thrice-weekly journey to Nasser Hospital in Khan Younis in the war-ravaged Gaza Strip.

The elderly Palestinian sits in a wheelchair mounted on a donkey-drawn cart, with an oxygen cylinder and a small fan beside him, as he makes his way from his tent in the Al-Mawasi area to the dialysis centre.

“Since January 2024 until now, I have been undergoing dialysis sessions three times a week,” he said. “I suffer a lot because of transportation as I travel in a cart pulled by a donkey under the scorching sun, and thank God, what can we do? I have no other choice.”

Near-daily ordeal

Access to the hospital has become part of his daily struggle, given the destruction of infrastructure, the lack of transportation and the continued difficult humanitarian conditions in the Strip since the Hamas-Israel war erupted in 2023.

Even with the October 2025 ceasefire, Gaza’s health system is still operating at limited capacity, according to the World Health Organization (WHO).

Israeli attacks and widespread damage to health facilities, along with restrictions on the entry of medical supplies, continue to impede the provision of healthcare at a time when patients with chronic diseases need regular, uninterrupted treatment, WHO said.

Mr. Hajji’s suffering reflects the reality for hundreds of kidney failure patients in the Gaza Strip, where obstacles facing health facilities have increased pressure on dialysis services.

Harsh test of survival

For Mr. Hajji, challenges remain travelling to and from the centre, where the treatment itself becomes a harsh test of survival.

During the journey his grandson, Saif, stops repeatedly to re-attach the wheelchair to the platform because of the bumpy roads.

“There is great suffering along the way due to the heat of the sun and the rough roads,” Saif explained. “We have to stop every 50 metres to adjust the position of my grandfather’s wheelchair, and we arrive at the hospital exhausted and in immediate need of oxygen.”

Limited resources

After a difficult trip, Saif helps transfer his grandfather from his wheelchair to a bed at the dialysis centre in the Nasser Medical Complex. Other patients line up waiting their turn at the available machines while the medical staff try to cope with increasing numbers and limited resources.

The elderly Mr. Hajji then begins his dialysis session as a health worker monitors his condition during the treatment, which lasts between three and five hours. 

“It is very difficult, especially with the high temperatures, so I had to bring a fan with me, and I also need to fill the oxygen cylinder daily,” Mr. Hajji explained.

Lack of equipment

The lack of equipment exacerbates the suffering of patients, said Hamza Abu Raya, one of the centre’s employees.

“We are under a lot of pressure on the dialysis machines, many of which are worn out,” he said. “We also suffer from a shortage of treatment supplies, including bicarbonate, in addition to the unavailability of the drug Eprex for a long time, which increases the suffering of patients.”

Shortages of fuel, spare parts and medical supplies are common, according to the UN Office for the Coordination of Humanitarian Affairs (OCHA). These critical problems are compounded by the continued spread of infectious diseases and the increasing pressure on existing health facilities.

Meanwhile, health partners continue to operate services to the maximum extent possible.

Another journey home

After the treatment session, Mr. Hajji is helped back into his wheelchair.

The frail Gazan then waits outside the hospital gates for the same donkey-led cart ride back to his tent, a journey that he repeats three times a week.

New Permanent Representative of Cyprus Presents Credentials to the Director-General of the United Nations Office at Geneva

Source: United Nations – Geneva

Μaria Papakyriakou, the new Permanent Representative of the Republic of Cyprus to the United Nations Office at Geneva, today presented her credentials to Tatiana Valovaya, the Director-General of the United Nations Office at Geneva.

Prior to her appointment to Geneva, Ms. Papakyriakou had been serving since 2021 as Ambassador of Cyprus to Germany.

She has held several high-level positions throughout her career in the Cypriot foreign service, including Director for Strategic Policy Planning, Diplomatic Advisor to the Minister of Defence, Director for Multilateral Affairs and International Organizations, Director of the Permanent Secretary’s Office, and Security Policy Director.

She also served as Ambassador of Cyprus to Denmark with parallel accreditation to Iceland from 2014 to 2018, as Political Counsellor in the Cyprus High Commission to the United Kingdom from 2006 to 2010, and as Political Officer at the Embassy of Cyprus in Germany in her first foreign posting from 1999 to 2004, including as Deputy Head of Mission for the last two years.  She joined the Ministry of Foreign Affairs in 1997.

Ms. Papakyriakou was born in Limassol, Cyprus. She holds graduate and postgraduate degrees in European studies from the Université d’Aix-Marseille III, France, and a pre-doctorate degree in political science from the Université Robert Schuman, Strasbourg, and the Institut d’Études Politiques de Strasbourg, France.  In addition to her native Greek, she speaks English, French and German fluently, and is proficient in Italian.  She is married to Cypriot diplomat Evangelos Savva and has two daughters.

___________

Produced by the United Nations Information Service in Geneva for use of the media; 
not an official record. English and French versions of our releases are different as they are the product of two separate coverage teams that work independently.

 

CR26.024E

Strengthening World Heritage Management and Climate Resilience in Pacific SIDS

Source: United Nations

In collaboration with ICCROM, UNESCO supported the organization of the International Course on Managing World Heritage: People Nature Culture (PNC), held in Suzhou, China, from 26 May to 4 June 2026. In the framework of the project Sustainable Islands: Building Heritage Disaster and Climate Resilience of Small Island Developing States in the Pacific Region, generously supported by the UNESCO/Republic of Korea Funds-in-Trust, UNESCO supported the participation of heritage professionals from six Pacific Small Island Developing States (SIDS): Fiji, Kiribati, Nauru, Papua New Guinea, Samoa and Tonga.

The ten-day course brought together 34 participants from around the world to strengthen capacities for integrated and people-centred heritage management.

Throughout the course, participants worked with two World Heritage properties from the Pacific region as case studies: Levuka Historical Port Town in Fiji and the Kuk Early Agricultural Site in Papua New Guinea. Using the latest Managing World Heritage Resource Manual and the Enhancing Our Heritage Toolkit 2.0 (EOH 2.0), participants assessed the value and attributes, factors affecting the properties, examined management systems, and explored practical approaches to disaster risk management, climate action and community engagement.

Through lectures, expert presentations, group discussions, field exercises and peer learning activities, participants explored the heritage place approach and reflected on how integrated management can strengthen both heritage conservation and community resilience.

© UNESCO / Xiangling Chen

“The course helped me better understand place-based approaches to heritage management, focusing on the conservation and enhancement of the multiple values of heritage places within their broader social, environmental, cultural and economic contexts. The knowledge and skills gained through this training will strengthen my capacity to document, protect and manage cultural and natural heritage sites in Samoa in close collaboration with local communities.”

© UNESCO / Xiangling Chen

“What I found most valuable was learning from other participants and reflecting on the importance of communities and traditional landowners. Rather than telling people what to do, we need to build trust and work together to support the protection of heritage places.”

© UNESCO / Xiangling Chen

“These approaches will be particularly useful for the management of the Kuk Early Agricultural Site and other heritage places we are working on. They will help us better manage community expectations, and I intend to use the tools introduced during the course as a practical checklist to strengthen our management planning.”

The course established a strong foundation for the next phase of the implementation of the project supported by the Korea Heritage Service via the UNESCO/Republic of Korea Funds-in-Trust. The knowledge, tools and professional networks developed through the training will support participating countries in strengthening disaster preparedness, climate adaptation and the sustainable management of heritage places across the Pacific region.

UNESCO thanks the Republic of Korea for its support in strengthening the protection of World Heritage sites in the Pacific SIDS.

Republic of Korea to provide over USD 3 million in support of World Heritage (2026–2030)

Source: United Nations

The Republic of Korea, through the Korea Heritage Service (KHS), has confirmed a continued voluntary contribution of KRW 5 billion to UNESCO for the period 2026–2030, with annual instalments of KRW 1 billion. This renewed support was reaffirmed at UNESCO Headquarters in Paris in the presence of Mr Huh Min, Administrator of the Korea Heritage Service (KHS); Mr Nayef H. Al-Fayez, Assistant Director-General for Culture; and H.E Jihee Kim, Ambassador and Permanent Delegate of the Republic of Korea to UNESCO, further strengthening a longstanding partnership spanning more than 25 years. This contribution follows a previous commitment of KRW 5.8 billion (USD 3,845,858) made between 2021 and 2025.

Cooperation under the KHS–UNESCO partnership will focus on World Heritage capacity-building, including inclusive heritage interpretation; technical assistance for World Heritage sites in the Korean Peninsula; and support for transboundary and regional cooperation across all regions.

Additional areas include preparatory assistance for future transboundary nominations, particularly for under-represented States Parties; support for the implementation of the Climate Action Policy for World Heritage; and broader activities related to protection, conservation, promotion, training, and management of World Heritage properties.

I would like to express UNESCO’s appreciation to the Republic of Korea, in particular to the Korea Heritage Service, for their sustained commitment and generous support, which continue to contribute significantly to the safeguarding of World Heritage and the strengthening of international cooperation.”

The partnership also covers coordination and implementation activities, including missions, under UNESCO/KHS Funds-in-Trust projects.

Government of Nepal and World Food Programme showcase school meals as a pathway to sustainable development

Source: World Food Programme

KATHMANDU, Nepal – The Government of Nepal and the United Nations World Food Programme (WFP) today launched two reports that highlight the remarkable progress made in strengthening food security, nutrition, education, climate resilience and social protection through strong national leadership and partnerships.

The two publications – the Journey of the National Mid-Day Meals Programme and WFP’s Annual Country Report 2025 – document Nepal’s development achievements and its transition from partner supported interventions to nationally owned systems that improve the lives of millions of people. Together, they demonstrate how sustained investments, partnerships and strong government leadership have contributed to building resilient institutions and advancing progress toward the Sustainable Development goals. 

“The achievements celebrated today reflect the power of partnership” noted Riaz Lodhi, WFP Representative and Country Director in Nepal. “Together with the Government of Nepal, development partners, and communities, WFP has helped advance solutions that strengthen food security, improve nutrition, build resilience and support human capital development.” 

The Journey of the National Mid-Day Meals Programme in Nepal chronicles more than five decades of Nepal’s school meals programme. Beginning in 1967 as a small initiative to address classroom hunger, it has now evolved into one of the country’s largest social protection programmes, reaching nearly three million children across all 77 districts and becoming fully financed by the Government of Nepal in 2025.

The report highlights the programme’s contribution to improved school enrolment, attendance, retention and nutrition outcomes, while also strengthening local food systems through the Home-Grown School Feeding approach that connects schools with local smallholder farmers through cooperatives.

‘’Finland is proud to support Nepal’s education sector through the School Sector Education Plan and Home-Grown School Feeding programme,” said H.E. Petri Puhakka, Ambassador of Finland to Nepal. “School meals in Nepal are not just about feeding children: they bring together schools, local governments, parents and farmer groups; and thus, creating a shared commitment to children’s wellbeing and education.’’

U.S. Embassy Nepal Chargé d’Affaires Scott Urbom said, “The best development investments deliver results far beyond their original purpose. School meals improve education and nutrition while creating reliable markets for Nepali farmers, cooperatives, and local businesses. The U.S. Department of Agriculture has proudly partnered with Nepal on this effort since 2005 because a healthier, better educated, and more prosperous Nepal is also a stronger partner for the United States, creating new opportunities for trade, investment, and cooperation between our countries.”

Speaking at the launch, Hon. Dr. Gunakar Bhatta, Vice Chair of National Planning commission, emphasized that “investing in children remains the national priority and strengthening school meals is strengthening the foundation of Nepal’s future prosperity”. He noted that school meals are strategic investment that simultaneously advances education, nutrition, agriculture, and local economic development, contributing to country’s long-term human capital development.

Building on the progress achieved through national ownership of the programme, Hon. Mr. Bel Bahadur Rana Magar, Minister of Social Development, Sudurpaschim Province, noted that the nationalization of the Mid-Day Meals Programme demonstrates what can be achieved through strong government leadership, sustained partnership, and innovation. He echoed WFP’s contribution in strengthening local food systems and creating market opportunities for women and local farmers through stronger links with schools, while reaffirming the Government’s commitment to building resilient systems that benefit children, communities, and future generations.

The publication also outlines Nepal’s ambition to expand the programme up to grade eight and increase coverage to as many as 4.5 million children in the coming years, further reinforcing school meals as a cornerstone of the country’s social protection and human capital development agenda.

Furthermore, the Annual Country Report 2025 highlights WFP’s support to more than 438,000 people through programmes focused on emergency preparedness and response, school meals, nutrition, climate resilience, sustainable livelihoods and food systems transformation. Among these achievements, the Home-Grown School Feeding approach benefited more than 208,000 students across Nepal, strengthening links between schools, farmers and local markets.

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Three New Countries Join the World Heritage List: A Major Milestone for Africa and SIDS

Source: UNESCO World Heritage Centre

The 48th session of the World Heritage Committee, held in Busan, Republic of Korea, marks a historic milestone for Africa and Small Island Developing States (SIDS). With the inscription of three new properties located in the Comoros, São Tomé and Príncipe, and South Sudan, three countries have joined the World Heritage List for the first time.

This achievement reflects the sustained efforts undertaken by UNESCO and its partners, as part of the implementation of the Priority Africa initiative, to make the World Heritage List more representative and ensure that it better reflects the world’s cultural and natural richness and diversity.

The inscription of this property, including its placement on the World Heritage List in Danger, strengthens our resolve to work even more closely with UNESCO and the international community to conserve its Outstanding Universal Value for the benefit of present and future generations. Through this inscription, South Sudan joins the family of World Heritage nations. This inscription is not only a victory for our people but also a contribution to humanity’s shared heritage and our collective responsibility to protect it.

When the World Heritage Strategy for Africa (2022–2029) was adopted by the World Heritage Committee in 2021, twelve African countries had no properties inscribed on the World Heritage List. Five years later, that number was cut in half.

These achievements are part of a broader momentum driven by UNESCO Director-General Khaled El-Enany, aimed at strengthening support for the 26 States Parties that are still not represented on the World Heritage List, as reflected in the recent World Heritage Strategy for Small Island Developing States (SIDS) 2026–2034, adopted by the World Heritage Committee at its 48th session.

Each site that joins the List brings a new perspective on human history and enriches our collective understanding of the world. From the Medinas of the Historic Sultanates of the Comoros to the Roças of Sao Tome and Principe, and the Boma-Badingilo Migratory Landscape in South Sudan, these inscriptions illustrate the diversity of experiences, knowledge systems, traditions and ecosystems that shape our planet. They serve as a reminder of how essential it is to continue efforts to identify, protect and keep our shared heritage alive.

27 July 2026 News release WHO: Integration, innovation and community leadership key to ending HIV, hepatitis and STIs

Source: World Health Organisation

The World Health Organization (WHO) today launched a new report assessing progress in implementing the Global Health Sector Strategies (GHSS) on HIV, viral hepatitis and sexually transmitted infections (STIs) for 2022–2030.

Released during the 26th International AIDS Conference (AIDS 2026) and ahead of World Hepatitis Day (28 July), the report highlights significant achievements and persistent challenges in the global response to these epidemics.

“This report tells two stories. It demonstrates what is possible when countries invest in health, communities and science. But it also shows how quickly progress can be undone with funding disruptions, humanitarian emergencies and persistent inequalities,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “Over the next five years, we must build integrated, resilient health systems that reach those furthest behind.”

By the end of 2025, an estimated 32 million people living with HIV were receiving treatment and since 2010, new HIV infections have fallen by 42% and AIDS-related deaths by 57%. Yet 9 million people still lack access to life-saving HIV treatment, and new infections continue to rise in several regions, particularly among key populations including men who have sex with men, sex workers, people who inject drugs, transgender people and people in prisons.

Progress has also been made in the response to viral hepatitis. Since 2015, annual hepatitis B infections have decreased by 32%, and hepatitis C-related deaths have fallen by 12% globally. Despite these gains, viral hepatitis remains one of the world’s deadliest infectious diseases, claiming an estimated 1.3 million lives in 2024, with mortality continuing to rise.

Progress in the global response to STIs has been mixed. Countries have strengthened national policies and improved syphilis screening and treatment in pregnancy, while HPV vaccination coverage has increased modestly. At the same time, STI rates are rising in several countries and communities, while there is growing resistance to antibiotics used to treat gonorrhoea.

Remaining challenges

Despite progress, major gaps continue to hinder efforts to eliminate HIV, viral hepatitis and STIs by 2030.

For HIV, reductions in international donor funding in 2025 disrupted prevention programmes in several countries, including access to pre-exposure prophylaxis (PrEP). Although some governments have stepped in to sustain services, preliminary data indicate that PrEP use has declined in a number of countries and communities.

For viral hepatitis, deaths linked to hepatitis B have increased by 17% since 2015. Diagnosis and treatment coverage remain low, particularly for hepatitis B, despite the availability of highly effective medicines that could prevent millions of deaths. As countries prepare to mark World Hepatitis Day under the theme “Hepatitis: Let’s Break It Down,” the report highlights the urgent need to remove the financial, social and systemic barriers that continue to limit access to hepatitis prevention, testing, treatment and care for millions of people.

The global STI response remains off track due to rising STI incidence, increasing antimicrobial resistance, and insufficient coverage of HPV vaccination and cervical cancer screening. Persistent gaps in surveillance, diagnostics, funding and health information systems further constrain countries’ ability to monitor the epidemic and scale up effective prevention, testing and treatment services.

Priorities for accelerating progress towards 2030

The report identifies integration as one of the greatest opportunities to accelerate progress. Countries reporting the strongest results are increasingly delivering services for HIV, viral hepatitis and STIs through primary health care, together with services for tuberculosis, sexual and reproductive health, maternal and child health and noncommunicable diseases.

Eliminating mother-to-child transmission of HIV, syphilis and hepatitis B remains a key priority. Encouragingly, a growing number of countries are applying for WHO validation of elimination, demonstrating that success is within reach when integrated maternal and child health services are strengthened.

Further gains can be achieved by expanding digital health solutions, strengthening interoperable surveillance and health information systems, scaling up multi-disease testing platforms and ensuring equitable access to innovations. These include improved diagnostics, quality-assured STI testing and long-acting prevention technologies such as WHO-recommended twice-yearly injectable lenacapavir. Lenacapavir is now being introduced in 10 countries and rollout is planned in a further 14. WHO’s recommendation on doxycycline post-exposure prophylaxis (doxycycline PEP) also offers a promising new opportunity to reduce bacterial STIs among populations at substantial risk.

Strengthening community leadership and embedding community-generated data into national monitoring systems can improve accountability, inform programme improvements and help ensure services reach those who are most often left behind.

To support countries in strengthening responses, WHO has released its first consolidated HIV service delivery guidelines bringing together the latest evidence-based recommendations to help countries organize HIV prevention, testing, treatment and long-term care. WHO has also published HIV surveillance guidance, designed to improve routine HIV surveillance systems and enhance the use of national health data for public health action.

“This assessment is more than a progress report; it is a practical guide for action for the second half of this strategy period,” said Dr Tereza Kasaeva, Director of WHO’s Department for HIV, TB, Hepatitis and STIs. “It highlights where countries are succeeding, where progress is stalling, and where investments can have the greatest impact. Together with our new consolidated HIV service delivery and HIV surveillance guidance, WHO is equipping countries with practical tools to strengthen programmes today and reach the people and communities who need them most.”

The report is published shortly after the adoption of the 2026 United Nations High-Level Meeting Political Declaration on HIV/AIDS, providing timely evidence to support implementation of commitments made by Member States.

Editor’s note

The Global Health Sector Strategies on HIV, viral hepatitis and sexually transmitted infections 2022–2030 were adopted by the World Health Assembly in 2022. They provide a common framework for countries to accelerate progress towards ending HIV, viral hepatitis and sexually transmitted infections as public health threats by 2030, while advancing universal health coverage, primary health care and health equity.